PDF | Libidibia ferrea, popularly known as “pau ferro” or “jucá”, is an important medicinal plant employed for the treatment of various ailments in. Genus: Libidibia (formerly known as Ceasalpinia). species: ferrea. Family: Fabaceae. Common Name: Leopard tree, Brazilian Ironwood. Description. Unarmed tree, to 15 m. Bark very distinctive, smooth, grey, pealing to reveal paler patches. Leaves 2-pinnate; pinnae in pairs, each with

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National Center for Biotechnology InformationU. CE did not show significant cytotoxic activity for either cell line.

First, LF aqueous extract was tested in visceral nociception induced by acetic acid, which demonstrated a significant analgesic effect Figure 1.

Coelho1 M. Retrieved from ” https: To better characterize what peripheral and central pathways libidigia LPLF was affecting, abdominal writhing test with the administration of different inhibitors was performed Figure 6. Nitric oxide derived from iNOS is involved in various pathological conditions such as inflammation and autoimmune diseases leading to tissue damage [ 31 ]. Biochemical and Biophysical Research Communications.

BioMed Research International

In a previous approach, Carvalho et al. Antinociceptive action demonstrated in fertea present study supports, at least partly, the ethnomedical uses of this plant and complements previous studies of this plant. It penetrates easily into damaged cells staining them blue, while the intact ones remain colorless, allowing determination of living and dead cell percentages. Donor mice were anaesthetized for tumor suctioning, and the ascitic form of the tumor was introduced under the right axilla of the receptor animals.


Libidibia ferrea

Pauferrol A, a novel chalcone trimer with a cyclobutane ring from Caesalpinia ferrea mart exhibiting DNA topoisomerase II inhibition and apoptosis-inducing activity. Articles with ‘species’ microformats. Anti-inflammatory evaluation of gardenia extract, geniposide and genipin. Analgesic Activity—Acetic Acid-Induced Writhing Response There are different routes to evaluate nociception; however, the assay using intraperitoneally acetic acid was the chosen approach.

Libidibia ferrea – Useful Tropical Plants

The nitrite content in the exudates was quantified using Griess reagent since nitric oxide NO synthesis by inducible nitric oxide synthase iNOS is increased in inflammation and frrrea to cellular injury. Osmium tetroxide test revealed that most of the totality of lipids observed was mainly unsaturated and predominantly observed in the cotyledon Figure 2 din the macrosclereids, and in the thicker cell walls of the fibers Figures 2 e – 2 f.

Prefers fertile, well drained soil and full sun. The control groups received the same volume, 0. Very distinctive dappled bark, smooth, grey, pealing to reveal paler patches. LF presented also a majority of unsaturated fatty acids which are represented as linoleic, oleic, linolenic, and palmitoleic acid, similar to C. It libidibix well known that the intraperitoneal administration of agents that irritate serous membranes, such as acetic acid, causes a stereotypical behavior in mice characterized by abdominal contractions, movements of the body as a whole, twisting of dorsoabdominal muscles, and a decrease in motor activity and coordination [ 38 ].

It has been demonstrated that the cholinergic system is involved in antinociceptive mechanisms, by 1 the activation of the GABAergic system [ 40 ]; 2 Muscarinic receptors mAChR mediation on spinal and 3 supraspinal sites [ 4142 ]; 4 inhibition enhancement of nicotinic receptors in the spinal dorsal horn [ 43 ]; 5 peripheral mAChR [ 44 ] or by interaction with the opioid system; however, this correlation is still not well elucidated.


Shade, Ornamental park or street tree, libidiiba consideration should be made to plant away from underground pipes or sewers as roots will invade.

Libidibia ferrea

Table of Contents Alerts. Both preparations revealed anti-inflammatory and antinociceptive activities, corroborating the pharmacological basis of L.

Articles from Evidence-based Complementary libidkbia Alternative Medicine: Studies on succinate-tetrazolium reductase system—III. On the other hand, their low toxicity allows the use of CE and F80 with a degree of safety ferrez other situations. Libidibia ferrea is a known popular used plant for treatment of different pain related injuries.

In last, result demonstrating the effect of LPLF in abdominal writhing test with presence of celecoxib is due to a peripheral and central synergism, but it also might indicate a selective COX-2 anti-inflammatory action [ 4950 ].

All efforts were made to minimize the number of animals used and their suffering. Subscribe to Table frrea Contents Alerts. Retrieved 23 June Antitumor Activity F80 showed a tumor growth inhibition of 8.

Views Read Edit View history. Anti-inflammatory, analgesic and antipyretic effects of methanol extract from Bauhinia racemosa stem bark in animal models. View at Google Scholar R. Table 1 Evaluation of anti-inflammatory activity of standard drugs dexamethasone, piroxicam and indomethacinCE, and F80 on carrageenan-induced peritonitis in pretreated mice.

Cell Viability — Trypan Blue 0. Animal models of nociception.